| Date | Time | Opponent | City | Location | Media | Score | Results |
|---|---|---|---|---|---|---|---|
| 8/30/2008 | 11:00 am |
Akron Opener |
Madison WI | Camp Randall |
Big Ten Network |
W 38-17 | 1-0-0 |
| 9/6/2008 | 11:00 am | Marshall | Madison WI | Camp Randall |
Big Ten Network |
2-0-0 | |
| 9/13/2008 | 9:30 pm | Fresno State | Fresno CA | Bulldog Stadium | ESPN2 | W 13-10 | 3-0-0 |
| 9/20/2008 |
Bye Week |
N/A | |||||
| 9/27/2008 | 2:30 pm | Michigan | Ann Arbor MI | Michigan Stadium | ABC, ESPN | L 25-27 | 3-1-0 |
| 10/4/2008 | 7:00 pm | Ohio State | Madison WI | Camp Randall | ABC | L 17-20 | 3-2-0 |
| 10/11/2008 | 7:00 pm | Penn State | Madison WI | Camp Randall | ESPN | L 7-48 | 3-3-0 |
| 10/18/2008 | 11:00 am | Iowa | Iowa City IA | Kinnick Stadium |
Big Ten Network |
L 16-38 | 3-4-0 |
| 10/25/2008 | 11:00 am |
Illinois Homecoming |
Madison WI | Camp Randall | ESPN | W 27-17 | 4-4-0 |
| 11/1/2008 | 11:00 am | Michigan State | East Lansing MI | Spartan Stadium | ESPN 2 | L 24-25 | 4-5-0 |
| 11/8/2008 | 11:00 am | Indiana | Bloomington IN | Memorial Stadium |
Big Ten Network |
W 55-20 | 5-5-0 |
| 11/15/2008 | 2:30 am | Minnesota | Madison WI | Camp Randall | ABC, ESPN | W 35-32 | 6-5-0 |
| 11/22/2008 | 2:30 am | Cal Poly | Madison WI | Camp Randall |
Big Ten Network |
W 36-35 |
7-5-0 |